Cost · Not a partner
One month, no commitment
$279/mo, month to month
The cheapest single month with no commitment. The lower monthly rates below need a longer plan.
| Drug | Month one | Each month after |
|---|---|---|
| Compounded semaglutide | $279 | $279 |
| Compounded tirzepatide | $379 | $379 |
| Brand semaglutide | $1,299 | $1,299 |
| Brand tirzepatide | $1,399 | $1,399 |
| Plan | Per month | Charged today |
|---|---|---|
Month to month (list price)SourceSemaglutide Injection Prepared by a licensed 503A U.S. pharmacy $139 $279/mo 50% off Billed monthly.Tryozi's home page · read September 2026 | $279 | $279 |
12 weeks paid upfront (3 four-week cycles)Source$219/mo Billed once, today: $657 for the full 12-week plan.Tryozi's home page · read September 2026 | $219 | $657 |
24 weeks paid upfront (6 four-week cycles)Source$199/mo Billed once, today: $1,194 for the full 24-week plan.Tryozi's home page · read September 2026 | $199 | $1,194 |
52 weeks paid upfront (13 four-week cycles, about 12 months)Source$149/mo Billed once, today: $1,937 for the full 52-week plan.Tryozi's home page · read September 2026 | $149 | $1,937 |
Two prices on its own pages
Tryozi prints two prices for compounded semaglutide: $139 Home hero (“Just $139”) and the Monthly plan card, under the September 50%-off banner and $279 The Monthly plan card, the list price printed beside $139. We rank it on $279 because the $139 is September's half-price offer, the tirzepatide card limits that same offer to the first four weeks, and all three prepaid plans cost more per month than $139.
The pricing section promises “Your monthly price doesn't jump as your dose increases.” The monthly card shows $139 beside a $279 list price under the September “50% off” banner and doesn't say how many months the cut lasts. Prepaid plans ship every 4 weeks.
| Plan | Per month | Charged today |
|---|---|---|
Month to month (after the first 4 weeks)Source$189 for your first 4 weeks, then $379/mo.Tryozi's home page · read September 2026 | $379 | $379 |
12 weeks paid upfront (3 four-week cycles)Source$319/mo Save 16% vs monthly Billed once, today: $957 for the full 12-week plan.Tryozi's home page · read September 2026 | $319 | $957 |
24 weeks paid upfront (6 four-week cycles)Source$299/mo Save 21% vs monthly Billed once, today: $1,794 for the full 24-week plan.Tryozi's home page · read September 2026 | $299 | $1,794 |
52 weeks paid upfront (13 four-week cycles, about 12 months)Source$249/mo Save 34% vs monthly Billed once, today: $3,237 for the full 52-week plan.Tryozi's home page · read September 2026 | $249 | $3,237 |
The first four weeks cost $189 under the “First month 50% off” label, then $379 a month. Dose changes don't change the figure, per the same promise that covers semaglutide.
| Plan | Per month | Charged today |
|---|---|---|
Ozempic, month to monthSourceOzempic® Brand-name prescription medication $1,299 Billed monthly.Tryozi's home page · read September 2026 | $1,299 | $1,299 |
Ozempic, sold as a Novo Nordisk brand-name pen. The card shows one figure and no dose ladder, and the 12-, 24- and 52-week tabs leave it unchanged.
| Plan | Per month | Charged today |
|---|---|---|
Zepbound, month to monthSourceZepbound® Brand-name prescription medication $1,399 Billed monthly.Tryozi's home page · read September 2026 | $1,399 | $1,399 |
Zepbound from Eli Lilly, one printed figure on every plan tab.
| Plan | Charged at once | Same months, paid monthly | Difference |
|---|---|---|---|
| 12 weeks paid upfront (3 four-week cycles) · compounded semaglutide | $657 | $837 | −$180 |
| 24 weeks paid upfront (6 four-week cycles) · compounded semaglutide | $1,194 | $1,674 | −$480 |
| 52 weeks paid upfront (13 four-week cycles, about 12 months) · compounded semaglutide | $1,937 | $3,348 | −$1,411 |
| 12 weeks paid upfront (3 four-week cycles) · compounded tirzepatide | $957 | $1,137 | −$180 |
| 24 weeks paid upfront (6 four-week cycles) · compounded tirzepatide | $1,794 | $2,274 | −$480 |
| 52 weeks paid upfront (13 four-week cycles, about 12 months) · compounded tirzepatide | $3,237 | $4,548 | −$1,311 |
The last two columns are our arithmetic, not Tryozi's: the plan's charge against the same number of months bought one at a time at Tryozi's month-to-month price. A prepay only saves that much if you stay on the drug for the whole term.
The service, the checks and who should skip Tryozi are in the Tryozi review. To price a plan line by line with any membership and fee added, use the real cost calculator; it reads the same ladder. How the advertised figure compares with every other company's is on the September 2026 Price Gap Index.
More reviews on the index; the rules behind them are on how we review.