Answer · read September 2026
The drug is Lilly's price almost everywhere. The fee on top is the markup.
Lilly's own price plus a fee of $49 to $149 a month. 11 of the 12 companies here print Lilly's $299 for the 2.5 mg starting dose, and each adds its own charge. At the top, Ro, Hims and LifeMD add $149, so a starting month is $448, 50% over LillyDirect by our math.
What this piece found
12 companies whose own pages print a self-pay Zepbound price, all of them at or above Lilly's. Lilly sells the vial and the KwikPen straight to self-pay patients through LillyDirect at $299 for 2.5 mg, $399 for 5 mg and $449 for 7.5 mg to 15 mg, the last on condition you refill within 45 days. Miss that window and 7.5 mg is $499 and 10 mg to 15 mg is $699. Lilly counts a month as 28 days.
Across every company reviewed here, 85 list brand tirzepatide (Zepbound or Mounjaro). 16 price it at Lilly's $299 starting month, and 19 price a pen at $1,000 or more, which is closer to Lilly's list price than to its self-pay price. Those figures come from each company's own review, dated there; the brand tirzepatide page lists them all.
Between $348 and $448 at the 2.5 mg starting dose, for the companies that charge a monthly fee. The drug is the same in every row; the fee is the whole difference.
| Company | Drug, 2.5 mg | Fee | A month, all in | Over LillyDirect |
|---|---|---|---|---|
| LillyDirectNo membership; you bring the prescription | $299 | $0 | $299 | Baseline |
| RoRo Body, monthly plan | $299 | $149/mo | $448 | $149 (50%) |
| HimsWeight Loss Membership | $299 | $149/mo | $448 | $149 (50%) |
| LifeMDProgram and provider fee | $299 | $149/mo | $448 | $149 (50%) |
| NoomNoom Med, brand path | $299 | $129/mo | $428 | $129 (43%) |
| MeasuredMembership | $299 | $99/mo | $398 | $99 (33%) |
| Zappy HealthMonthly subscription | $349 | $99/mo | $448 | $149 (50%) |
| WeightWatchersMed+, 6-month plan (the shortest) | $299 | $84/mo | $383 | $84 (28%) |
| Mochi HealthMembership | $299 | $79/mo | $378 | $79 (26%) |
| PreventiveMDMonthly membership | $299 | $49/mo | $348 | $49 (16%) |
| Walgreens$49 per visit, no subscription | $299 | $49 a visit | $299 plus the fee | Depends on visits |
| Amazon One MedicalCare from $39 | $299 | $39 a visit | $299 plus the fee | Depends on visits |
| ZipHealth$79 clinical service and support fee; how often isn't stated on the page | $299 | $79 | $299 plus the fee | Not stated |
A month, all in, and the markup are by our math: the company's printed drug price plus its monthly fee, against Lilly's $299. First-month promotions are left out because each applies once (Ro, Hims, LifeMD and Noom start at $39; WeightWatchers at $25). Mochi’s older $39 introductory quote is historical: a banner read October 15 advertises $79 off the first month of its one-month plan, with separate terms not evaluated here. WeightWatchers publishes no monthly Med+ plan, so its row uses the 6-month plan, the shortest it sells; Ro's membership falls to $74 a month if you prepay a year. Every price was read on the company's own page on September 27, 2026.
Zappy Health is the one row where the drug itself costs more: $349 at 2.5 mg on its page, against $299 on Lilly's. Zappy says the medication is billed through Eli Lilly. If Lilly bills its own price, the markup is the $99 subscription alone; ask Zappy which figure you'll be charged before you start.
The drug goes to $449 and the fee stays where it was. Most people don't stay at 2.5 mg, which Lilly calls a starting dose that isn't approved for maintenance. At 7.5 mg to 15 mg Lilly charges $449 while you refill within 45 days, and Ro, Measured, Walgreens and ZipHealth print that same $449. With Ro's monthly membership, that month is $598, by our math, 33% over LillyDirect.
The other companies print only a starting price. Several of them hand the prescription to Lilly, so Lilly's ladder is the likely bill, but it isn't what their own pages say, and the refill window is Lilly's rule: a late refill puts 10 mg to 15 mg back at $699 whichever company wrote the prescription.
For 8 of the 12, the page with the price also says where the drug comes from. Noom's vials are “fulfilled through LillyDirect”, PreventiveMD's medication is “paid directly to LillyDirect”, Measured's cash-pay path runs “through LillyDirect”, ZipHealth's KwikPen “ships directly from Eli Lilly” and Zappy Health's medication is “through Eli Lilly”. Ro says its cash prices match LillyDirect's. Walgreens and Amazon One Medical send the prescription to a pharmacy.
Hims, LifeMD, WeightWatchers and Mochi Health print a Zepbound price without saying on the same page where it's filled. Who fills your prescription covers what each company says elsewhere.
When the company does something LillyDirect doesn't. On price alone it never comes out ahead: the drug is the same price and the fee is added. The non-price reasons are real, though. LillyDirect sells to self-pay patients and needs a prescription from a clinician you already have. If you don't have one, a company is how you get one. Ro, LifeMD, Measured and WeightWatchers say they'll check insurance for Zepbound or do the prior-authorization paperwork, and a covered prescription isn't priced by this table at all. Does anyone take your insurance? covers who says what.
If you need few visits, a per-visit company can cost less over a year than a monthly fee. One $49 Walgreens visit a month matches the lowest monthly fee here, PreventiveMD's $49; three a month, $147, is close to the top. How often you'll need a visit is a question for the company before you start.
By the name on the product and who ships it. Brand Zepbound is sold as a single-dose vial or a KwikPen and comes from Lilly or a pharmacy you choose. Compounded tirzepatide is made by a compounding pharmacy, is not FDA-approved, and is usually priced on a flat monthly plan with the drug included. Does the company name the molecule? covers the companies that don't say which one you're buying, and the tirzepatide premium compares both against semaglutide.
Each sentence below is quoted verbatim from the publisher's own page, read on September 27, 2026. The monthly totals and markups above are ours.
| Publisher | What they say, verbatim | Where, and when |
|---|---|---|
| Eli Lilly (Zepbound pricing information) | Available through Zepbound self-pay, Zepbound is offered as a 4‑count single‑dose vial (0.5mL) and a single‑patient‑use KwikPen (2.4mL, 0.6mL/dose) in doses of 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg and 15mg, with direct‑to‑patient pricing of $299, $399, $499, $699, $699 and $699 respectively.Lilly's self-pay price for the vial and KwikPen, by dose | LillyDirect's Zepbound pageRead September 2026 |
| LillyDirect | For 7.5 mg, 10 mg, 12.5 mg and 15 mg doses, prices reflect monthly cost with Zepbound Journey Program. Regular prices will apply if prescription is not refilled within 45 days ($499 for 7.5mg, $699 for 10mg, $699 for 12.5mg, and $699 for 15mg).The $449 offer at 7.5 mg to 15 mg, and the refill rule | LillyDirect's Zepbound pageRead September 2026 |
| LillyDirect | Month is defined as 28-days and 1 single-patient-use KwikPen.What Lilly calls a month | LillyDirect's Zepbound pageRead September 2026 |
| Ro | 2.5 mg $299 5 mg $399 7.5 mg Save $50 $449 with offer 10 mg to 15 mg Save $150 $449 with offerRo's Zepbound KwikPen prices, by dose | Ro's pricing pageRead September 2026 |
| Ro | Yes! Ro offers FDA-approved GLP-1s at the lowest cash pay prices available—the same pricing as NovoCare®, LillyDirect®, and TrumpRx.Ro on matching Lilly's price | Ro's pricing pageRead September 2026 |
| Ro | After your first month, you’ll be charged $74-149/mo depending on the plan you choose.The Ro Body membership | Ro's pricing pageRead September 2026 |
| Hims | Price includes medication only, if prescribed. An active Hims Weight Loss Membership is required ($39 for the first month, auto-renews at $149/month thereafter).Hims's Zepbound price and membership | Hims' weight loss pageRead September 2026 |
| Hims | Zepbound® Vial From $299/mo†Hims's Zepbound cards | Hims' weight loss pageRead September 2026 |
| LifeMD | Zepbound® Vial Starting At $299LifeMD's Zepbound price | LifeMD's weight management pageRead September 2026 |
| LifeMD | Our program starts as low as $39 for your first month, and just $149 a month thereafter with the flexibility to cancel anytime.LifeMD's program fee | LifeMD's weight management pageRead September 2026 |
| WeightWatchers | Self pay starting at $299/mo.WeightWatchers' Zepbound card | WeightWatchers' weight loss medication pageRead September 2026 |
| WeightWatchers | After the first month, membership continues for $74/mo (12-month plan) or $84/mo (6-month plan) for the remainder of your applicable plan term. Cost of GLP-1 medications not included.The WW Med+ membership | WeightWatchers' weight loss medication pageRead September 2026 |
| Noom | Access authentic Zepbound vials as low as $299/mo, fulfilled through LillyDirectNoom's Zepbound price and who fills it | Noom's Zepbound pageRead September 2026 |
| Noom | $39 to get started, then $129/month for ongoing care.Noom Med's fee for the brand path | Noom's Zepbound pageRead September 2026 |
| Mochi Health | Zepbound® As low as $299Mochi's Zepbound card | Mochi Health's home pageRead September 2026 |
| Mochi Health | After the first month, monthly membership fee increases to $79/month.Mochi's membership | Mochi Health's home pageRead September 2026 |
| Measured | Current self-pay pricing through LillyDirect ranges from $299/month (2.5mg starting dose) to $449/month (higher doses), depending on your dose.Measured's Zepbound price and who fills it | Measured's Zepbound pageRead September 2026 |
| Measured | Measured membership is $99/monthMeasured's membership | Measured's Zepbound pageRead September 2026 |
| Zappy Health | $99/month Monthly Subscription All doses Billed monthly Cost of medication is separate and through Eli Lilly $349/mo (2.5 mg), $499-$649/mo (5-10 mg)Zappy's Zepbound plan | Zappy Health's Zepbound vials pageRead September 2026 |
| ZipHealth | 2.5mg Starting at $299 5mg Starting at $399 7.5mg Starting at $449 10mg Starting at $449 12.5mg Starting at $449 15mg Starting at $449ZipHealth's Zepbound KwikPen prices, by dose | ZipHealth's Zepbound pageRead September 2026 |
| ZipHealth | From $299* + Clinical service and support fee $79ZipHealth's fee and who ships the pen | ZipHealth's Zepbound pageRead September 2026 |
| ZipHealth | Your Zepbound KwikPen ships directly from Eli Lilly to your door.Who ships ZipHealth's pen | ZipHealth's Zepbound pageRead September 2026 |
| PreventiveMD | Monthly membership fee $49 + medication starting at $299/mo per month , paid directly to LillyDirect®.PreventiveMD's fee, and who is paid for the drug | PreventiveMD's Zepbound pageRead September 2026 |
| Walgreens | $49 per visit, no subscription needed.Walgreens Weight Management's visit fee | Walgreens Weight Management's weight loss.jsp pageRead September 2026 |
| Walgreens | Regular price for 1-month supplies of the Zepbound KwikPen (or vial) is $299 for 2.5 mg, $399 for 5 mg, $499 for 7.5 mg, $699 for 10 mg, $699 for 12.5 mg, and $699 for 15 mg.The Zepbound prices Walgreens prints | Walgreens Weight Management's weight loss.jsp pageRead September 2026 |
| Amazon One Medical | Zepbound Kwikpen Pen injector · 28 day supply Starting dose (2.5 mg) $299Amazon Pharmacy's KwikPen price, and the care fee | Amazon One Medical's b0g21y5r7m pageRead September 2026 |
| Amazon One Medical | Care from $39Amazon One Medical's care fee | Amazon One Medical's b0g21y5r7m pageRead September 2026 |
Some companies named here pay us a commission when a reader starts care through a marked link. The one marked link on this page is one of them, picked by rule and disclosed beside it. Nothing above is ordered by who pays: the price table runs LillyDirect first, then companies by monthly fee from highest to lowest, then the per-visit ones, then ZipHealth, whose fee has no stated frequency. Who pays us · how we review · every review.